With a team of highly specialized experts, the DDIC assists in the commercialization of modern therapeutic products, working on translational research and development in the areas of Biopharmaceutics, Drug Delivery, Quality Control, and Regulatory Sciences.
The DDIC provides specialized prototypes of novel and conventional dosage forms through testing and production of clinical trial materials in its pharmaceutical test laboratory and Health Canada licensed cleanroom. The Centre’s unique infrastructure allows clinical testing support to take place from study design to finished product with access to a rich and diverse pool of experts.
Services
Researchers: Novel delivery systems, Nano Formulations, Design and Proof of Concept Studies
Pharmaceutical Industry: Product Research and Design, Quality Control, Regulatory Affairs, Analytical Testing, Drug Release Testing, Performance Testing, Production (Liquid, Gel, Semi Solid, Solid), Product Life Cycle Management
Clinical Investigators: Joint Clinical Research, Clinical Trial Dosage Forms (Design and Development)
Students and Trainees: Industrial Pharmacy, Regulatory Sciences
Facilities
GMP Compliant Classified Cleanrooms Facility: ISO 6 (Class 1000) and ISO 7 (Class 10,000): for production and packaging, includes a clean room gowning area, clean room formulation facility, clean room filling area
Sterile Products Development Laboratory: for formulation of drug products
GLP Compliant Quality Control Laboratory: for testing of drug products
Prototype Laboratory: for executing project designs
Equipment
Product Development Equipment: Analytical Balances, Blister packaging, Capsule filling equipment (000, 00, 0, 1), Comill, Containment chamber, Customized labelling, Double Cone Blender, Emulsification equipment, Fluid Bed Dryer, Fluid Bed Granulator, Freeze Dryer, Granulators, Grinders for controlled size reduction, Mixers and Blenders, Ointment maker and dispenser, Ointment Mill, Rotary Tablet Press with instrumentation, Screw Capping Machine, Single Cone Blender, Spray Dryer, Suppository Maker, Tablet Counting Machine, Tablet Press and De-Duster, Tube Filler, Water Purification System, 3D-Chromotographer
Quality + Performance Characterization Equipment: Capsule Filler, Disintegration Testing Apparatus, Dissolution Testing Apparatuses (1, 2), Flow through Cell (for performance testing of special dosage forms), Franz Cell (for performance testing of special dosage forms), Friability Tester, HPLC System, HPLC Systems for chemical analysis, Soxhlet Extraction Apparatus, Stability Chambers, Tablet Hardness Tester, Thermal Activity Monitor, Thermal Conductivity Tester, Weight Checker
The DDIC’s state-of-the-art equipment is capable of processing small to medium quantities of active pharmaceutical ingredients.
It provides researchers with the ability to engage in development and performance analysis of a variety of special and conventional dosage forms ranging from tablets and capsules to microemulsions, ointments, creams and nanoparticles.
The centre adheres to the standards for Good Manufacturing Practices outlined by Health Canada and offers stability testing, according to the protocols of the International Conference on Harmonization (ICH), and received a Health Canada Site License for manufacturing, processing, and packaging in 2009 and has had the license renewed annually.
